反应详情

DIAD (0.625 ml, 3.21 mmol) was added to a mixture of 5-bromo-1-(4-methoxybenzyl)-1,2-dihydropyridazine-3,6-dione (500 mg, 1.607 mmol), ((1S,2S)-2-(5-methoxypyridin-2-yl)cyclopropyl)methanol (288 mg, 1.607 mmol) and PPh3 (843 mg, 3.21 mmol) in THF (15 ml) at 0° C.