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HRID542600

反应详情

EQUATION

反应方程式

HRID 542600 的结构方程式

REACTANTS

反应物

3
结构：NN.O
HCID24654

Hydrazine hydrate (1:1)

H6N2O

结构：O=C1Nc2cc(Cl)ccc2C1=O
HCID241331

6-Chloroisatin

C8H4ClNO2

结构：CC[O-].[Na+]
HCID2723922

Ethanol, sodium salt

C2H5NaO

PRODUCTS

生成物

1
结构：O=C1Cc2ccc(Cl)cc2N1
HCID736344

6-Chlorooxindole

C8H6ClNO

收率 42.5%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Reaction of 36.2 g of 6-chloroisatin with hydrazine hydrate followed by sodium ethoxide in ethanol, substantially according to C above, afforded 14.2 g of 6-chloro-2-oxindole, mp 196°-198° C.