huagongshe.com
HRID55130

反应详情

EQUATION

反应方程式

HRID 55130 的结构方程式

REACTANTS

反应物

3
结构：Oc1cccc(C(F)(F)F)c1
HCID7376

3-(Trifluoromethyl)phenol

C7H5F3O

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CSc1cc(Cl)nc(OCc2ccsc2)c1
HCID53958130

未命名化合物

PRODUCTS

生成物

1
结构：CSc1cc(OCc2ccsc2)nc(Oc2cccc(C(F)(F)F)c2)c1
HCID54481631

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Cu][I]
催化剂HCID24350

Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

CuI

结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

To a solution containing meta-trifluoromethylphenol (1.60 g, 0.0024×4.1 mol), sodium hydride (0.29 g, (ca.60% in mineral oil), 0.0024×3.0 mol) and CuI (0.22 g, 0.0024×0.5 mol) in dimethylformamide, 2-chloro-4-methylmercapto-6-(3-thienylmethyloxy)pyridine (0.64 g, 0. 0024 mol) was added and the resultant solution was refluxed for about 6 hours.

WORKUP

后处理

  1. additionwas added