Dimethylformamide → HCID 86734583, compound

HRID 597489Notes

Reaction equation

HRID 597489 reaction equation
[Na].[SH:2]C1OC2C=CC=CC=2N=1.[C:12]([CH2:14][CH2:15][N:16]([CH2:23][CH2:24][O:25][C:26](=O)[CH2:27]Cl)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)#[N:13].[C:30]1(C)[C:31](C)=[CH:32][CH:33]=[CH:34][CH:35]=1.C[N:39](C)[CH:40]=[O:41]>>[C:12]([CH2:14][CH2:15][N:16]([CH2:23][CH:24]([C:40]1[O:41][C:31]2[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=2[N:39]=1)[O:25][C:26](=[S:2])[CH3:27])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)#[N:13]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 7237O-XyleneHCID 5360545SodiumHCID 86734584HCID 86734584, compoundHCID 1784182821,3-benzoxazole-2-thiol

Product 1

HCID 86734583HCID 86734583, compound

Procedure

10 parts of sodium salt of 2-mercaptobenzoxazole and 13.32 parts of N-(2-cyanoethyl)-N-(α-chloroacetoxyethyl)-aniline in 200 parts of xylene and 40 parts of dimethyl formamide is boiled under reflux for 24 hours. It is worked up in the manner described in Instruction-1 to furnish N-(2-cyanoethyl)-N-(benzoxazolyl-2-thioacetoxy ethyl) aniline having the formula ##STR17##

Workup

  1. temperatureunder reflux for 24 hours

Sources & evidence

ORD record
ord-69c966c6df6f44beb8398db142eec96b
Source dataset
uspto-grants-1977_03
Patent number
US04014864

Reaction notes

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