反应详情

Prepare essentially as described in EXAMPLE 15 using palladium(II) acetate (0.002 g, 0.01 mmol), tri-o-tolylphosphine (0.06 g, 0.02 mmol), copper (I) iodide (0.001 g, 0.005 mmol), 1-chloro-4-iodobenzene (0.24 g, 1 mmol) and 5-vinylnicotinonitrile, (prepared essentially as described in PREPARATION 51), (0.195 g, 1.5 mmol) at 100° C. for 7 h to give the title compound (0.170 g, 70%).

1. customPrepare essentially
2. custom(prepared essentially
3. customas described in PREPARATION 51), (0.195 g, 1.5 mmol) at 100° C. for 7 h