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HRID641785

反应详情

EQUATION

反应方程式

HRID 641785 的结构方程式

REACTANTS

反应物

2
结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

结构：Nc1ccnc(Cl)c1N
HCID285736

2-chloropyridine-3,4-diamine

C5H6ClN3

PRODUCTS

生成物

1
结构：Oc1nc2ccnc(Cl)c2[nH]1
HCID178517330

未命名化合物

收率 86.5%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

1.1 A solution of 17.23 g of 3,4-diamino-2-chloropyridine and 19.46 g of 1,1′-carbonyldiimidazole in THF is stirred at room temperature for 16 hours. The product is separated off and dried, giving 17.6 g of 4-chloro-3H-imidazo[4,5-c]pyridin-2-ol (“1”).

WORKUP

后处理

  1. customThe product is separated off
  2. customdried