反应详情

Phosphorous oxychloride (0.15 mol) in 100 ml. THF are mixed dropwise at 10° C. with bis-chloroethylamine (0.1 mol) in 100 ml. THF and triethylamine (0.15 mol). After ending of the reaction (TLC verification), triethylamine hydrochloride is filtered off and the filtrate, after the addition of 50 ml. toluene, evaporated. The oily residue is immediately further reacted.

1. filtrationis filtered off
2. additionthe filtrate, after the addition of 50 ml
3. customtoluene, evaporated
4. customThe oily residue is immediately further reacted