Dimethylformamide → 7-Chloro-thieno[3,2-b]pyridin-2-yl-morpholin-4-yl-methanone

HRID 666178Notes

Reaction equation

HRID 666178 reaction equation
[CH2:15]1[CH2:16][O:17][CH2:18][CH2:19][NH:20]1.[CH2:21]([N:22]([CH:23]([CH3:24])[CH3:25])[CH:26]([CH3:27])[CH3:28])[CH3:29].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9]([C:11](=[O:12])[O-:13])[s:10]2.[Cl:30][CH2:31][Cl:32].[Cl:38][C:39]([C:40]([Cl:41])=[O:42])=[O:43].[Li+:14].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9]([C:11](=[O:13])[N:20]1[CH2:15][CH2:16][O:17][CH2:18][CH2:19]1)[s:10]2

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8083MorpholineHCID 28486Lithium ionHCID 65578Oxalyl chlorideHCID 81531DiisopropylethylamineHCID 178524058HCID 178524058, compound

Product 1

HCID 222786227-Chloro-thieno[3,2-b]pyridin-2-yl-morpholin-4-yl-methanone

Sources & evidence

ORD record
ord-c0599550a2884b7bbdfb5f8157b906b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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