HRID669838

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID769

Bicarbonate Ion

CHO3-

HCID923

Sodium ion

Na+

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID8857

Ethyl acetate

C4H8O2

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID55281683

6-(1-Azetidinyl)-3-pyridinamine

C8H11N3

结构：C[Si](C)(C)c1ccc2c(c1)cc(C(=O)O)n2Cc1cccc(F)c1

HCID58100953

未命名化合物

PRODUCTS

生成物

结构：C[Si](C)(C)c1ccc2c(c1)cc(C(=O)Nc1ccc(N3CCC3)nc1)n2Cc1cccc(F)c1

HCID44199404

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3fd07c5d734e4d79884c206c74490c63
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (3/10)

反应 SMILES

[CH3:23][Si:24]([c:25]1[cH:26][c:27]2[cH:28][c:29]([C:42](=[O:43])[OH:44])[n:30]([CH2:34][c:35]3[cH:36][c:37]([F:41])[cH:38][cH:39][cH:40]3)[c:31]2[cH:32][cH:33]1)([CH3:45])[CH3:46].[CH3:2][N:3]([CH3:4])[CH2:5][CH2:6][CH2:7][N:8]=[C:9]=[N:10][CH2:11][CH3:12].[CH3:68][CH2:69][O:70][C:71]([CH3:72])=[O:73].[ClH:1].[NH2:47][c:48]1[cH:49][n:50][c:51]([N:54]2[CH2:55][CH2:56][CH2:57]2)[cH:52][cH:53]1.[Na+:62].[O-:58][C:59]([OH:60])=[O:61].[O:63]=[CH:64][N:65]([CH3:66])[CH3:67].[OH:13][n:14]1[c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]2[n:21][n:22]1>>[CH3:23][Si:24]([c:25]1[cH:26][c:27]2[cH:28][c:29]([C:42](=[O:43])[NH:47][c:48]3[cH:49][n:50][c:51]([N:54]4[CH2:55][CH2:56][CH2:57]4)[cH:52][cH:53]3)[n:30]([CH2:34][c:35]3[cH:36][c:37]([F:41])[cH:38][cH:39][cH:40]3)[c:31]2[cH:32][cH:33]1)([CH3:45])[CH3:46]