1-Bromo-3-chloropropane → 3-(3-Chloropropyl)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Reaction equation
[Br:17][CH2:18][CH2:19][CH2:20][Cl:21].[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41].[CH:27]([N:28]([CH2:29][CH3:30])[CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]23[CH2:10][NH:11][CH2:12][CH:13]2[CH2:14]3)[cH:7][cH:8]1)([F:15])[F:16]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]23[CH2:10][N:11]([CH2:18][CH2:19][CH2:20][Cl:21])[CH2:12][CH:13]2[CH2:14]3)[cH:7][cH:8]1)([F:15])[F:16]Participants
6
Sources & evidence
- ORD record
- ord-95429eacf9bc40e2854b4f1becdb6dd0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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