Tetrahydrofuran → HCID 68517676, compound

HRID 674810Notes

Reaction equation

HRID 674810 reaction equation
[C:51]([O:52][CH3:53])([CH3:54])([CH3:55])[CH3:56].[CH3:34][Si:35]([CH3:36])([CH3:37])[C:38]#[N:39].[Cl+3:40]([O-:41])([O-:42])([O-:43])[O-:44].[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:22]([F:23])([F:24])[F:25])[CH2:10][C:11]([c:14]3[cH:15][cH:16][c:17]([CH:18]=[O:19])[cH:20][cH:21]3)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1.[Li+:45].[NH2:26][CH2:27][c:28]1[n:29][cH:30][cH:31][cH:32][cH:33]1.[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:22]([F:23])([F:24])[F:25])[CH2:10][C:11]([c:14]3[cH:15][cH:16][c:17]([CH:18]([NH:26][CH2:27][c:28]4[n:29][cH:30][cH:31][cH:32][cH:33]4)[C:38]#[N:39])[cH:20][cH:21]3)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 15413tert-Butyl methyl etherHCID 195092-PyridinemethanamineHCID 28486Lithium ionHCID 82115Trimethylsilyl cyanideHCID 123351PerchlorateHCID 86643376HCID 86643376, compound

Product 1

HCID 68517676HCID 68517676, compound

Sources & evidence

ORD record
ord-4f2254e8c3934fbeae685c14eb389657
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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