Chloride → 1-(Benzyloxy)-2-bromo-4-fluorobenzene

HRID 682200Notes

Reaction equation

HRID 682200 reaction equation
[Br:16][CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[Br:1][c:2]1[c:3]([OH:9])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[C:10](=[O:11])([O-:12])[O-:13].[CH2:27]([N+:28]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH3:43].[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[Cl-:25].[I-:26].[K+:14].[K+:15].[Na+:24]>>[Br:1][c:2]1[c:3]([O:9][CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

11

Reactant 10

HCID 312ChlorideHCID 813Potassium Cation2×HCID 923Sodium ionHCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 30165Iodide IonHCID 6054722-Bromo-4-fluorophenol

Product 1

HCID 216409031-(Benzyloxy)-2-bromo-4-fluorobenzene

Sources & evidence

ORD record
ord-de4046810afb4ca79340f07aab457ea8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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