Hydrochloric Acid → 3-(2-Methylbenzo[b]furan-5-yl)prop-2-yn-1-ol

HRID 690380Notes

Reaction equation

HRID 690380 reaction equation
[CH2:23]([C:24]#[CH:25])[OH:26].[ClH:27].[Cu:33][I:34].[I:1][c:2]1[cH:3][c:4]2[c:5]([o:6][c:7]([CH3:9])[cH:8]2)[cH:10][cH:11]1.[N:12]12[CH2:13][CH2:14][CH2:15][N:16]=[C:17]1[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]2.[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[OH2:112].[cH:35]1[cH:36][cH:37][c:38]([P:39]([Pd:40]([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[P:79]([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)([c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)[c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[cH:110][cH:111]1>>[c:2]1([C:25]#[C:24][CH2:23][OH:26])[cH:3][c:4]2[c:5]([o:6][c:7]([CH3:9])[cH:8]2)[cH:10][cH:11]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 962WaterHCID 7859Propargyl alcoholHCID 8028TetrahydrofuranHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 38560465-Iodo-2-methylbenzofuranHCID 178420554HCID 178420554, compound

Product 1

HCID 671466183-(2-Methylbenzo[b]furan-5-yl)prop-2-yn-1-ol

Sources & evidence

ORD record
ord-835d2818cbaf4757950d8f761cc06f4f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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