Dimethylformamide → 2-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-phenylpent-4-enyl)thiazolo[5,4-b]pyridine
Reaction equation
[Br:45][CH2:46][CH2:47][CH:48]=[CH2:49].[CH2:40]1[CH2:41][CH2:42][CH2:43][O:44]1.[CH3:31][Si:32]([N-:33][Si:34]([CH3:35])([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Li+:30].[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:29])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([CH2:22][c:23]5[cH:24][cH:25][cH:26][cH:27][cH:28]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1.[O:50]=[CH:51][N:52]([CH3:53])[CH3:54]>>[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:29])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([CH:22]([c:23]5[cH:24][cH:25][cH:26][cH:27][cH:28]5)[CH2:43][CH2:42][CH:41]=[CH2:40])[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-052ed3d6891c47dd8b4bb18a7e2b84f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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