Triethylamine → 3-[2-(trans-4-Pentylcyclohexyl)ethynyl]-6-propylpyridazine

HRID 693229Notes

Reaction equation

HRID 693229 reaction equation
[Br:1][c:2]1[n:3][n:4][c:5]([CH2:8][CH2:9][CH3:10])[cH:6][cH:7]1.[C:11](#[CH:12])[CH:13]1[CH2:14][CH2:15][CH:16]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:17][CH2:18]1.[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:31][O:32][C:33]([CH3:34])([CH3:35])[CH3:36].[Cu:78][I:79].[Pd:37]([Cl:38])[Cl:39].[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1.[c:59]1([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[cH:73][cH:74][cH:75][cH:76][cH:77]1>>[c:2]1([C:12]#[C:11][CH:13]2[CH2:14][CH2:15][CH:16]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:17][CH2:18]2)[n:3][n:4][c:5]([CH2:8][CH2:9][CH3:10])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 15413tert-Butyl methyl etherHCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 143657611-Ethynyl-4-pentylcyclohexaneHCID 233171853-Bromo-6-propylpyridazine

Product 1

HCID 233171743-[2-(trans-4-Pentylcyclohexyl)ethynyl]-6-propylpyridazine

Sources & evidence

ORD record
ord-9fa510bca67e4768a3514057dfcb08f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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