Acetic Acid → [2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclopropyl-acetic acid
Reaction equation
[CH2:1]([N:2]([N:3]=[O:4])[C:9]([CH:10]([CH:11]1[CH2:12][CH2:13]1)[n:14]1[c:15](-[c:25]2[cH:26][cH:27][c:28]([Cl:31])[cH:29][cH:30]2)[n:16][c:17]2[c:18]1[cH:19][c:20]([F:24])[c:21]([F:23])[cH:22]2)=[O:32])[c:5]1[cH:6][cH:7][cH:8][cH:33][cH:34]1.[CH3:47][C:48](=[O:49])[OH:50].[ClH:40].[Li+:37].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH-:36].[OH2:35].[OH2:46].[OH:38][OH:39]>>[C:9]([CH:10]([CH:11]1[CH2:12][CH2:13]1)[n:14]1[c:15](-[c:25]2[cH:26][cH:27][c:28]([Cl:31])[cH:29][cH:30]2)[n:16][c:17]2[c:18]1[cH:19][c:20]([F:24])[c:21]([F:23])[cH:22]2)([OH:32])=[O:35]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-5611583276a74655a0a6fbd9c78974fb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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