Hydrochloric Acid → 1-(6-Nitro-pyridin-3-yl)-azetidin-3-ol

HRID 695525Notes

Reaction equation

HRID 695525 reaction equation
[Br:7][c:8]1[cH:9][cH:10][c:11]([N+:14](=[O:15])[O-:16])[n:12][cH:13]1.[CH2:27]([N+:28]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH3:43].[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[CH3:51][N:52]([CH3:53])[C:54](=[O:55])[CH3:56].[CH:17]([N:18]([CH:19]([CH3:20])[CH3:21])[CH2:22][CH3:23])([CH3:24])[CH3:25].[ClH:6].[I-:26].[OH2:44].[OH:1][CH:2]1[CH2:3][NH:4][CH2:5]1>>[OH:1][CH:2]1[CH2:3][N:4]([c:8]2[cH:9][cH:10][c:11]([N+:14](=[O:15])[O-:16])[n:12][cH:13]2)[CH2:5]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 962WaterHCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 30165Iodide IonHCID 31374DimethylacetamideHCID 81531DiisopropylethylamineHCID 8176205-Bromo-2-nitropyridineHCID 15142903-Hydroxyazetidine

Product 1

HCID 592909581-(6-Nitro-pyridin-3-yl)-azetidin-3-ol

Sources & evidence

ORD record
ord-e4d4d9ce95754fda87a45c0758436141
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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