Hydrochloric Acid → N-[2-(6-Methoxy-2-methyl-1-oxo-4-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl]-1-(4-methoxyphenyl)cyclopropanecarboxamide

HRID 696424Notes

Reaction equation

HRID 696424 reaction equation
[CH3:25][O:26][c:27]1[cH:28][cH:29][c:30]([C:33]2([C:36](=[O:37])[OH:38])[CH2:34][CH2:35]2)[cH:31][cH:32]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:58][N:59]([CH3:60])[CH2:61][CH2:62][CH2:63][N:64]=[C:65]=[N:66][CH2:67][CH3:68].[CH3:69][N:70]([CH3:71])[CH:72]=[O:73].[ClH:1].[ClH:57].[NH2:2][CH2:3][CH2:4][c:5]1[n:6]([CH3:24])[c:7](=[O:23])[c:8]2[cH:9][cH:10][c:11]([O:21][CH3:22])[cH:12][c:13]2[c:14]1-[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1.[OH2:46].[OH:47][n:48]1[c:49]2[cH:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[NH:2]([CH2:3][CH2:4][c:5]1[n:6]([CH3:24])[c:7](=[O:23])[c:8]2[cH:9][cH:10][c:11]([O:21][CH3:22])[cH:12][c:13]2[c:14]1-[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[C:36]([C:33]1([c:30]2[cH:29][cH:28][c:27]([O:26][CH3:25])[cH:32][cH:31]2)[CH2:34][CH2:35]1)=[O:37]

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 855751-(4-Methoxyphenyl)cyclopropane-1-carboxylic acidHCID 114040673-(2-Aminoethyl)-6-methoxy-2-methyl-4-phenylisoquinolin-1-one

Product 1

HCID 11260220N-[2-(6-Methoxy-2-methyl-1-oxo-4-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl]-1-(4-methoxyphenyl)cyclopropanecarboxamide

Sources & evidence

ORD record
ord-ea6089d9fd524e72a6ace1ced9744405
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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