Hydrochloric Acid → 5-(2-(Tert-butyldimethylsilyloxy)ethyl)-2-chlorothiophene-3-carbaldehyde
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:8][CH2:9][CH2:10][c:11]1[s:12][c:13]([Cl:16])[cH:14][cH:15]1.[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[CH2:33]1[CH2:35][CH2:34][CH2:36][O:37]1.[CH3:22][C:23]1([CH3:24])[CH2:25][CH2:26][CH2:27][C:28]([CH3:29])([CH3:30])[NH:31]1.[ClH:32].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:8][CH2:9][CH2:10][c:11]1[s:12][c:13]([Cl:16])[c:14]([CH:36]=[O:37])[cH:15]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-896f50447281430485455b7daca418c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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