Tetrahydrofuran → HCID 57828221, compound

HRID 702430Notes

Reaction equation

HRID 702430 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([O:12][Si:13]([CH3:14])([CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19])[cH:8][c:9]2[cH:10][cH:11]1.[CH2:20]([CH2:21][C:22]#[CH:23])[NH:24][C:25]([O:26][CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)=[O:34].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[Cu:88][I:89].[Pd:47]([Cl:48])[Cl:49].[c:50]1([P:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:64][cH:65][cH:66][cH:67][cH:68]1.[c:69]1([P:70]([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[cH:83][cH:84][cH:85][cH:86][cH:87]1>>[c:2]1([C:23]#[C:22][CH2:21][CH2:20][NH:24][C:25]([O:26][CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)=[O:34])[cH:3][c:4]2[cH:5][cH:6][c:7]([O:12][Si:13]([CH3:14])([CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19])[cH:8][c:9]2[cH:10][cH:11]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 134730832-Bromo-6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]naphthaleneHCID 21185506HCID 21185506, compound

Product 1

HCID 57828221HCID 57828221, compound

Sources & evidence

ORD record
ord-bb771f9ff27a4d45977210759569ec32
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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