Triethylamine → HCID 62006965, compound

HRID 747687Notes

Reaction equation

HRID 747687 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[CH3:8][NH:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12].C(N(CC)CC)C.C(OCC)(=O)C>C1(C)C(C)=CC=CC=1>[CH3:8][N:9]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 122884-ChloropyridineHCID 95849Glycine, N-methyl-, ethyl ester

Product 1

HCID 62006965HCID 62006965, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

17 g (113 mmol) of 4-chloropyridine, 17 g (111 mmol) of ethyl (methylamino)acetate and 47 ml (333 mmol) of triethylamine were stirred in 350 ml of xylene at 130° C. for 24 hours. After the treatment with ethyl acetate as the extractant in an ordinary manner, the title compound was obtained.

Sources & evidence

ORD record
ord-81974470bfe646ada75627fef3aaac0e
Source dataset
uspto-grants-2008_07
Patent number
US07396844B1

Reaction notes

Loading…