Isopropanol → 3-Amino-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid

HRID 804169Notes

Reaction equation

HRID 804169 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]([C:14](=[O:15])[OH:16])([NH:17][C:18]([O:19][CH2:20][CH:21]2[c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]3-[c:28]3[c:29]2[cH:30][cH:31][cH:32][cH:33]3)=[O:34])[CH2:11][CH2:12][CH2:13]1.[C:39]([O:40][CH3:41])([CH3:42])([CH3:43])[CH3:44].[CH2:45]1[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1.[CH3:51][N:52]([CH3:53])[CH:54]=[O:55].[CH:35]([OH:36])([CH3:37])[CH3:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]([C:14](=[O:15])[OH:16])([NH2:17])[CH2:11][CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 3776IsopropanolHCID 6228DimethylformamideHCID 8082PiperidineHCID 15413tert-Butyl methyl etherHCID 27344081-((tert-butoxy)carbonyl)-3-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)piperidine-3-carboxylic acid

Product 1

HCID 247296423-Amino-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid

Sources & evidence

ORD record
ord-37cde37a9a10448ba4023fa3612b0726
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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