Hydrochloric Acid → tert-Butyl 3,5-bis(benzyloxy)-4-bromobenzoate

HRID 804469Notes

Reaction equation

HRID 804469 reaction equation
[C:27]([n:28]1[cH:29][cH:30][n:31][cH:32]1)([n:33]1[cH:34][cH:35][n:36][cH:37]1)=[O:38].[C:39]([CH3:40])([CH3:41])([CH3:42])[OH:43].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][c:16]([O:19][CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:17]1[Br:18].[CH2:44]1[CH2:45][CH2:46][C:47]2=[N:52][CH2:51][CH2:50][CH2:49][N:48]2[CH2:53][CH2:54]1.[ClH:55].[O:56]=[CH:57][N:58]([CH3:59])[CH3:60].[OH2:61]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([C:12]([O:13][C:39]([CH3:40])([CH3:41])[CH3:42])=[O:14])[cH:15][c:16]([O:19][CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:17]1[Br:18]

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 6386tert-ButanolHCID 682631,1'-CarbonyldiimidazoleHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 100247103,5-Bis(benzyloxy)-4-bromobenzoic acid

Product 1

HCID 10389923tert-Butyl 3,5-bis(benzyloxy)-4-bromobenzoate

Sources & evidence

ORD record
ord-7079abc7b2e64f30b92c71a3fed692a5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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