HRID806163

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID6344

Dichloromethane

CH2Cl2

HCID8857

Ethyl acetate

C4H8O2

HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

HCID81531

Diisopropylethylamine

C8H19N

HCID136469

4-Trifluoromethylpiperidine

C6H10F3N

结构：CC(C)(C)[Si](OC1CCC(C2CCN(Cc3c(Cl)cc(-c4ccc(C(=O)O)cc4)cc3Cl)C2=O)CC1)(c1ccccc1)c1ccccc1

HCID67355400

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)[Si](OC1CCC(C2CCN(Cc3c(Cl)cc(-c4ccc(C(=O)N5CCC(C(F)(F)F)CC5)cc4)cc3Cl)C2=O)CC1)(c1ccccc1)c1ccccc1

HCID67354701

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-775174dae9994912acf18d5d0454202d
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([CH:13]2[C:14](=[O:36])[N:15]([CH2:18][c:19]3[c:20]([Cl:35])[cH:21][c:22](-[c:26]4[cH:27][cH:28][c:29]([C:32](=[O:33])[OH:34])[cH:30][cH:31]4)[cH:23][c:24]3[Cl:25])[CH2:16][CH2:17]2)[CH2:11][CH2:12]1)([c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1)[c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[C:49]([n:50]1[cH:51][cH:52][n:53][cH:54]1)([n:55]1[cH:56][cH:57][n:58][cH:59]1)=[O:60].[CH3:84][CH2:85][O:86][C:87](=[O:88])[CH3:89].[CH:72]([N:73]([CH:74]([CH3:75])[CH3:76])[CH2:77][CH3:78])([CH3:79])[CH3:80].[Cl:81][CH2:82][Cl:83].[ClH:61].[F:62][C:63]([CH:64]1[CH2:65][CH2:66][NH:67][CH2:68][CH2:69]1)([F:70])[F:71]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([CH:13]2[C:14](=[O:36])[N:15]([CH2:18][c:19]3[c:20]([Cl:35])[cH:21][c:22](-[c:26]4[cH:27][cH:28][c:29]([C:32](=[O:34])[N:67]5[CH2:66][CH2:65][CH:64]([C:63]([F:62])([F:70])[F:71])[CH2:69][CH2:68]5)[cH:30][cH:31]4)[cH:23][c:24]3[Cl:25])[CH2:16][CH2:17]2)[CH2:11][CH2:12]1)([c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1)[c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1