Tetrahydrofuran → 1-Cyclopropyl-2-(2-fluorophenyl)ethan-1-one
Reaction equation
[CH3:12][N:13]([C:14](=[O:15])[CH:16]1[CH2:17][CH2:18]1)[CH3:19].[CH3:25][O:26][C:27]([CH3:28])([CH3:29])[CH3:30].[F:3][c:4]1[c:5]([CH2:6][Cl:7])[cH:8][cH:9][cH:10][cH:11]1.[I:2].[Mg:1].[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1>>[F:3][c:4]1[c:5]([CH2:6][C:14](=[O:15])[CH:16]2[CH2:17][CH2:18]2)[cH:8][cH:9][cH:10][cH:11]1Participants
7
Sources & evidence
- ORD record
- ord-6ca1e5bcb9c549da8d9a69683cc2fea9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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