Chloride → 1-cyclopropyl-N-[(2,4-dichlorophenyl)methyl]-3-methyl-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide

HRID 811349Notes

Reaction equation

HRID 811349 reaction equation
[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH:1]1([N:4]([C:5]([CH2:6][P:8](=[O:9])([O:10][CH2:11][CH3:12])[O:13][CH2:14][CH3:19])=[O:15])[CH:16]([C:17](=[O:7])[CH3:18])[C:20](=[O:21])[NH:22][CH2:23][c:24]2[c:25]([Cl:31])[cH:26][c:27]([Cl:30])[cH:28][cH:29]2)[CH2:2][CH2:3]1.[Cl-:33].[Li+:32].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[CH:1]1([N:4]2[C:5](=[O:15])[CH:6]=[C:17]([CH3:18])[CH:16]2[C:20](=[O:21])[NH:22][CH2:23][c:24]2[c:25]([Cl:31])[cH:26][c:27]([Cl:30])[cH:28][cH:29]2)[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 28486Lithium ionHCID 86644398Diethyl (2-{cyclopropyl[1-({[(2,4-dichlorophenyl)methyl]amino}-carbonyl)-2-oxopropyl]amino}-2-oxoethyl)phosphonate

Product 1

HCID 250296981-cyclopropyl-N-[(2,4-dichlorophenyl)methyl]-3-methyl-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide

Sources & evidence

ORD record
ord-4c106513446d4ae68fc6cc30ea0243a0
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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