Water → 5-{6-[3-(4-fluorophenyl)-1-trityl-1H-pyrazol-4-yl]quinazolin-4-yl}thio phen-2-sulfonic acid methyl-[2-(4-methylpiperazin-1-yl)ethyl]amide

HRID 812181Notes

Reaction equation

[CH3:55][N:56]1[CH2:57][CH2:58][NH:59][CH2:60][CH2:61]1.[CH3:62][CH2:63][N:64]([CH2:65][CH3:66])[CH2:67][CH3:68].[CH3:69][N:70]([CH3:71])[CH:72]=[O:73].[CH3:75][CH2:76][O:77][C:78](=[O:79])[CH3:80].[Cl:1][CH2:2][CH2:3][N:4]([S:5](=[O:6])(=[O:7])[c:8]1[s:9][c:10](-[c:13]2[n:14][cH:15][n:16][c:17]3[cH:18][cH:19][c:20](-[c:23]4[c:24](-[c:47]5[cH:48][cH:49][c:50]([F:53])[cH:51][cH:52]5)[n:25][n:26]([C:28]([c:29]5[cH:30][cH:31][cH:32][cH:33][cH:34]5)([c:35]5[cH:36][cH:37][cH:38][cH:39][cH:40]5)[c:41]5[cH:42][cH:43][cH:44][cH:45][cH:46]5)[cH:27]4)[cH:21][c:22]23)[cH:11][cH:12]1)[CH3:54].[OH2:74]>>[CH2:2]([CH2:3][N:4]([S:5](=[O:6])(=[O:7])[c:8]1[s:9][c:10](-[c:13]2[n:14][cH:15][n:16][c:17]3[cH:18][cH:19][c:20](-[c:23]4[c:24](-[c:47]5[cH:48][cH:49][c:50]([F:53])[cH:51][cH:52]5)[n:25][n:26]([C:28]([c:29]5[cH:30][cH:31][cH:32][cH:33][cH:34]5)([c:35]5[cH:36][cH:37][cH:38][cH:39][cH:40]5)[c:41]5[cH:42][cH:43][cH:44][cH:45][cH:46]5)[cH:27]4)[cH:21][c:22]23)[cH:11][cH:12]1)[CH3:54])[N:59]1[CH2:58][CH2:57][N:56]([CH3:55])[CH2:61][CH2:60]1