Water → 3-(4-Bromo-3-methylphenyl)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole

HRID 815990Notes

Reaction equation

HRID 815990 reaction equation
[Br:1][c:2]1[c:3]([CH3:11])[cH:4][c:5]([CH:6]=[N:7][OH:8])[cH:9][cH:10]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:41][N:42]([CH3:43])[CH:44]=[O:45].[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[Cl:12][N:13]1[C:14](=[O:15])[CH2:16][CH2:17][C:18]1=[O:19].[Cl:20][c:21]1[cH:22][c:23]([Cl:33])[cH:24][c:25]([C:27](=[CH2:28])[C:29]([F:30])([F:31])[F:32])[cH:26]1.[OH2:46]>>[Br:1][c:2]1[c:3]([CH3:11])[cH:4][c:5]([C:6]2=[N:7][O:8][C:27]([c:25]3[cH:24][c:23]([Cl:33])[cH:22][c:21]([Cl:20])[cH:26]3)([C:29]([F:30])([F:31])[F:32])[CH2:28]2)[cH:9][cH:10]1

Participants

8

Reactant 7

HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 31398ChlorosuccinimideHCID 231598231,3-Dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzeneHCID 738479544-Bromo-3-methylbenzaldehyde oxime

Product 1

HCID 231598123-(4-Bromo-3-methylphenyl)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole

Sources & evidence

ORD record
ord-0318b0268fba485eb8701967cdaf2188
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…