Bicarbonate Ion → 2-Aminomethyl-adamantan-2-ol

HRID 816143Notes

Reaction equation

HRID 816143 reaction equation
[Al+3:24].[C:18](=[O:19])([O-:20])[OH:21].[CH3:12][Si:13]([CH3:14])([CH3:15])[C:16]#[N:17].[CH:1]12[C:2](=[O:11])[CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2.[CH:40]([Cl:41])([Cl:42])[Cl:43].[Cl:29][CH2:30][Cl:31].[H-:23].[H-:26].[H-:27].[H-:28].[I-:37].[I-:39].[Li+:25].[Na+:22].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[Zn+2:38]>>[CH:1]12[C:2]([OH:11])([CH2:16][NH2:17])[CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2

Participants

13

Reactant 12

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6212ChloroformHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 30165Iodide Ion2×HCID 32051Zinc(2+)HCID 64151AdamantanoneHCID 82115Trimethylsilyl cyanideHCID 104727Aluminum CationHCID 166653Hydride4×

Product 1

HCID 2866492-Aminomethyl-adamantan-2-ol

Sources & evidence

ORD record
ord-b12832774bad4637a1625753df2c531d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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