Hydrochloric Acid → 3-Bromo-4-fluoroaniline

HRID 822862Notes

Reaction equation

HRID 822862 reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:31][CH2:32][O:33][C:34]([CH3:35])=[O:36].[Cl+:1]([O-:2])[O-:3].[ClH:15].[F:5][c:6]1[c:7]([Br:14])[cH:8][c:9]([CH:10]=[O:11])[cH:12][cH:13]1.[N-:17]=[N+:18]=[N-:19].[Na+:16].[Na+:4].[OH2:30].[S:20](=[O:21])(=[O:22])([OH:23])[OH:24]>>[F:5][c:6]1[c:7]([Br:14])[cH:8][c:9]([NH2:17])[cH:12][cH:13]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 962WaterHCID 1118Sulfuric AcidHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 33558AzideHCID 1736043-Bromo-4-fluorobenzaldehydeHCID 197148Chlorite

Product 1

HCID 27792863-Bromo-4-fluoroaniline

Sources & evidence

ORD record
ord-83cb4100825d45a9b350fc9eed04b88c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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