Acetonitrile → 5-(4-Chlorophenyl)-2-trimethylsilanylethynylpyridine

HRID 822878Notes

Reaction equation

HRID 822878 reaction equation
[C:8](#[CH:9])[Si:10]([CH3:11])([CH3:12])[CH3:13].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:28][C:29]#[N:30].[Cl:14][c:15]1[cH:16][cH:17][c:18](-[c:21]2[cH:22][cH:23][c:24]([I:27])[n:25][cH:26]2)[cH:19][cH:20]1.[Cu:36][I:37]>>[C:8](#[C:9][c:24]1[cH:23][cH:22][c:21](-[c:18]2[cH:17][cH:16][c:15]([Cl:14])[cH:20][cH:19]2)[cH:26][n:25]1)[Si:10]([CH3:11])([CH3:12])[CH3:13]

Participants

7

Reactant 6

HCID 6342AcetonitrileHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 859698495-(4-Chlorophenyl)-2-iodopyridine

Product 1

HCID 673636115-(4-Chlorophenyl)-2-trimethylsilanylethynylpyridine

Sources & evidence

ORD record
ord-c21a16fd9ddf4a039adff1fd2cd83d95
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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