HRID827415

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID312

Chloride

Cl-

2 次

HCID8028

Tetrahydrofuran

C4H8O

HCID9741

1,3-Difluorobenzene

C6H4F2

HCID11776

Triphenylphosphine

C18H15P

4 次

HCID14268

4-Bromopyridine

C5H4BrN

HCID23938

Palladium

HCID32051

Zinc (II) cation

Zn+2

HCID178418339

未命名化合物

PRODUCTS

生成物

HCID10899450

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ada48cd31e1f4c08851057055f9a6d24
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:14][c:15]1[cH:16][cH:17][n:18][cH:19][cH:20]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[Cl-:26].[Cl-:28].[F:6][c:7]1[cH:8][cH:9][cH:10][c:11]([F:12])[cH:13]1.[O:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1.[Pd:29].[Zn+2:27].[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1.[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1.[c:68]1([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[cH:82][cH:83][cH:84][cH:85][cH:86]1.[c:87]1([P:88]([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[cH:101][cH:102][cH:103][cH:104][cH:105]1>>[F:6][c:7]1[cH:8][cH:9][cH:10][c:11]([F:12])[c:13]1-[c:15]1[cH:16][cH:17][n:18][cH:19][cH:20]1