Hydroxyphenylacetic acid → Benzyl 2-(4-hydroxyphenyl)acetate

HRID 828265Notes

Reaction equation

HRID 828265 reaction equation
[Br:18][CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[Li+:12].[Li+:13].[O-:14][C:15](=[O:16])[O-:17].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30].[OH:1][C:2](=[O:3])[CH2:4][c:5]1[cH:6][cH:7][c:8]([OH:9])[cH:10][cH:11]1>>[O:1]=[C:2]([O:3][CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[CH2:4][c:5]1[cH:6][cH:7][c:8]([OH:9])[cH:10][cH:11]1

Participants

6

Reactant 5

HCID 127Hydroxyphenylacetic acidHCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 19660Carbonate IonHCID 28486Lithium ion2×

Product 1

HCID 11107524Benzyl 2-(4-hydroxyphenyl)acetate

Sources & evidence

ORD record
ord-af055a633bf04db9818a7b89115fef21
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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