Tetrahydrofuran → 2-Furan-2-yl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrazin-8-ylamine

HRID 829596Notes

Reaction equation

[Br:1][c:2]1[n:3][c:4]([NH2:16])[c:5]2[n:6]([cH:7]1)[n:8][c:9](-[c:11]1[o:12][cH:13][cH:14][cH:15]1)[n:10]2.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:17][Si:18]([CH3:19])([CH3:20])[C:21]#[CH:22].[Cu:28][I:29].[Pd:30]([Cl:31])[Cl:32].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[c:2]1([C:22]#[C:21][Si:18]([CH3:17])([CH3:19])[CH3:20])[n:3][c:4]([NH2:16])[c:5]2[n:6]([cH:7]1)[n:8][c:9](-[c:11]1[o:12][cH:13][cH:14][cH:15]1)[n:10]2