Methane → 2-Amino-5-chlorobenzoic acid

HRID 830960Notes

Reaction equation

[C:19].[Cl:1][c:2]1[cH:3][cH:4][c:5]([N+:11]([O-:12])=[O:13])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[O:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1.[Rh:20]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH2:11])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1

Participants

Reactant 4

HCID 297Methane

HCID 8028Tetrahydrofuran

HCID 172865-Chloro-2-nitrobenzoic acid

HCID 23948Rhodium

Product 1

HCID 124762-Amino-5-chlorobenzoic acid

Sources & evidence

ORD record: ord-884d0224f20c4f70b530a31927742777
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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