Bicarbonate Ion → 2-Chloro-3-(2,2,2-trifluoroethoxy)pyridine

HRID 835398Notes

Reaction equation

HRID 835398 reaction equation
[C:33](=[O:34])([OH:35])[O-:36].[CH3:15][S:16](=[O:17])(=[O:18])[OH:19].[Mg+2:20].[N:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32].[NH2:1][c:2]1[c:3]([Cl:8])[n:4][cH:5][cH:6][cH:7]1.[Na+:37].[O-:21][S:22](=[O:23])(=[O:24])[O-:25].[OH:9][CH2:10][C:11]([F:12])([F:13])[F:14]>>[c:2]1([O:9][CH2:10][C:11]([F:12])([F:13])[F:14])[c:3]([Cl:8])[n:4][cH:5][cH:6][cH:7]1

Participants

9

Reactant 8

HCID 769Bicarbonate IonHCID 888Magnesium CationHCID 923Sodium ionHCID 1117Sulfate IonHCID 6395Methanesulfonic AcidHCID 64092,2,2-TrifluoroethanolHCID 10906Tert-Butyl nitriteHCID 805282-Chloro-3-pyridylamine

Product 1

HCID 120567282-Chloro-3-(2,2,2-trifluoroethoxy)pyridine

Sources & evidence

ORD record
ord-2c97dfbb23a14c4793e379c2c6fde468
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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