1,2-Dichloroethane → 2-(Benzenesulfonyl-pyridin-2-yl-amino)-N-[3-(9-chloro-3-methyl-4-oxo-5H-isoxazolo[4,3-c]quinolin-5-yl)-cyclohexyl]-acetamide

HRID 835754Notes

Reaction equation

HRID 835754 reaction equation
[CH2:55]([Cl:56])[CH2:57][Cl:58].[CH3:64][N:65]([c:66]1[cH:67][cH:68][n:69][cH:70][cH:71]1)[CH3:72].[IH:1].[NH2:2][CH:3]1[CH2:4][CH:5]([n:9]2[c:10](=[O:24])[c:11]3[c:12]([c:13]4[c:14]([Cl:19])[cH:15][cH:16][cH:17][c:18]24)[n:20][o:21][c:22]3[CH3:23])[CH2:6][CH2:7][CH2:8]1.[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[OH:45][n:46]1[c:47]2[n:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1.[c:25]1([S:31](=[O:32])(=[O:33])[N:34]([c:35]2[n:36][cH:37][cH:38][cH:39][cH:40]2)[CH2:41][C:42](=[O:43])[OH:44])[cH:26][cH:27][cH:28][cH:29][cH:30]1>>[NH:2]([CH:3]1[CH2:4][CH:5]([n:9]2[c:10](=[O:24])[c:11]3[c:12]([c:13]4[c:14]([Cl:19])[cH:15][cH:16][cH:17][c:18]24)[n:20][o:21][c:22]3[CH3:23])[CH2:6][CH2:7][CH2:8]1)[C:42]([CH2:41][N:34]([S:31]([c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)(=[O:32])=[O:33])[c:35]1[n:36][cH:37][cH:38][cH:39][cH:40]1)=[O:43]

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 142844-(Dimethylamino)pyridineHCID 24841Hydrogen iodideHCID 181649HOAtHCID 14721802-[(Phenylsulfonyl)(2-pyridinyl)amino]acetic acidHCID 227137145-(3-Amino-cyclohexyl)-9-chloro-3-methyl-5H-isoxazolo[4,3-c]quinolin-4-one

Product 1

HCID 227141272-(Benzenesulfonyl-pyridin-2-yl-amino)-N-[3-(9-chloro-3-methyl-4-oxo-5H-isoxazolo[4,3-c]quinolin-5-yl)-cyclohexyl]-acetamide

Sources & evidence

ORD record
ord-a53efe7864284c23a546dabe2e3d04f4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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