反应详情

Potassium carbonate (13.5 g, 0.098 mol) followed by 1-iodopropane (9.56 mL, 0.098 mol) were added to a solution of 4-methyl-3-nitro-phenol (15 g, 0.098 mol) in DMF (100 mL). The mixture was stirred for 5 hours and then partitioned between H2O and EtOAc. The organic layer was washed with satd NaHCO3, brine, dried over Na2SO4 and concentrated to a clear oil (17.5 g).

1. custompartitioned between H2O and EtOAc
2. washThe organic layer was washed with satd NaHCO3, brine
3. dry with materialdried over Na2SO4
4. concentrationconcentrated to a clear oil (17.5 g)