Dimethylamine → HCID 59702349, compound

HRID 902564Notes

Reaction equation

HRID 902564 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:17]2[C:13](=[C:14]([S:19](Cl)=[O:20])[N:15]([CH3:18])[N:16]=2)[CH:12]=[CH:11][CH:10]=1.C[O:23][CH2:24][CH2:25][NH2:26].CNC.CN.N1CC[O:35]CC1.CN1CCNCC1.N(CCO)CCO>>[OH:23][CH2:24][CH2:25][NH:26][S:19]([C:14]1[N:15]([CH3:18])[N:16]=[C:17]2[C:13]=1[CH:12]=[CH:11][CH:10]=[C:9]2[C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])(=[O:20])=[O:35]

Participants

8

Reactant 7

HCID 674DimethylamineHCID 6329MethylamineHCID 80182-MethoxyethylamineHCID 8083MorpholineHCID 8113DiethanolamineHCID 531671-MethylpiperazineHCID 86597925HCID 86597925, compound

Product 1

HCID 59702349HCID 59702349, compound

Procedure

The following compounds were prepared from 7-(2,4-dichloro-phenyl)-2-methyl-2H -indazole-3-sulfinyl chloride in a similar fashion by replacing ethanolamine with 2-methoxyethylamine, dimethylamine, methylamine, morpholine, N-methylpiperazine and diethanolamine.

Sources & evidence

ORD record
ord-3f09a0267ed64f75998aa8abb8b26fab
Source dataset
uspto-grants-2008_04
Patent number
US07365211B2

Reaction notes

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