反应详情

温度

60 °C

A mixture of 3-nitrobenzylbromide (2 g), 3-bromo-5-ethoxy-4-hydroxy benzaldehyde (2.06 g), K2CO3 (2.55 g) and Bu4NI (186 mg) in DMF (50 ml) was stirred at 60° C. for 2 h. The reaction mixture was diluted with ethyl acetate and washed with water and brine. The organic layer was dried (MgSO4), filtered and concentrated in vacuo. The residue was recrystallized from heptane.

1. washwashed with water and brine
2. dry with materialThe organic layer was dried (MgSO4)
3. filtrationfiltered
4. concentrationconcentrated in vacuo
5. customThe residue was recrystallized from heptane