反应详情

温度

90 °C

A mixture of the product from step (i) (3.0 g), potassium carbonate (4.42 g) and benzyl bromide (3.90 ml) in DMF (40 ml) was heated at 90° C. for 14 h. The mixture was partitioned between water/ethyl acetate, the organics separated, dried and evaporated under reduced pressure. The residue was purified by chromatography on silica eluting with isohexane/diethylether 5:1, yield 6.3 g.

1. customThe mixture was partitioned between water/ethyl acetate
2. customthe organics separated, dried
3. customevaporated under reduced pressure
4. customThe residue was purified by chromatography on silica eluting with isohexane/diethylether 5:1, yield 6.3 g