反应详情

A mixture of the product from step (i) (4.95 g) and 5% platinum on carbon (0.400 g) and a few drops of 2M hydrochloric acid in ethyl acetate (30 ml) was hydrogenated under a pressure of 3 bar. The catalyst was removed by filtration through celite and the filtrate was evaporated under reduced pressure to a brown solid, which was triturated with diethyl ether to give a pink solid. Yield 1.28 g

1. customThe catalyst was removed by filtration through celite
2. customthe filtrate was evaporated under reduced pressure to a brown solid, which
3. customwas triturated with diethyl ether
4. customto give a pink solid