Hydrochloric Acid → 5-Bromo-2-fluoro-4-methylbenzaldehyde

HRID 933222Notes

Reaction equation

HRID 933222 reaction equation
[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([F:8])[cH:6][cH:7]1.[CH:10]([N-:11][CH:12]([CH3:13])[CH3:14])([CH3:15])[CH3:16].[ClH:23].[Li+:17].[O:18]=[CH:19][N:20]([CH3:21])[CH3:22].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1.[OH2:29]>>[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([F:8])[c:6]([CH:19]=[O:18])[cH:7]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 967432-Bromo-5-fluorotolueneHCID 5062348Diisopropylamide

Product 1

HCID 447549105-Bromo-2-fluoro-4-methylbenzaldehyde

Sources & evidence

ORD record
ord-3c3cd8ad6748492a98555593047218b6
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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