Dimethylformamide → HCID 57714116, compound
Reaction equation
[Br:17][c:18]1[c:19]([NH:26][CH2:27][C:28]([CH3:29])([CH3:30])[CH3:31])[n:20][c:21]([C:24]#[N:25])[n:22][cH:23]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][C:15]#[CH:16])[CH2:12][CH2:13]1.[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cu:85][I:86].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[Pd:44]([Cl:45])[Cl:46].[c:47]1([P:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:61][cH:62][cH:63][cH:64][cH:65]1.[c:66]1([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[cH:80][cH:81][cH:82][cH:83][cH:84]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][C:15]#[C:16][c:18]2[c:19]([NH:26][CH2:27][C:28]([CH3:29])([CH3:30])[CH3:31])[n:20][c:21]([C:24]#[N:25])[n:22][cH:23]2)[CH2:12][CH2:13]1Participants
8
Reactant 7
HCID 6228Dimethylformamide
HCID 8471Triethylamine
HCID 11776Triphenylphosphine2×
HCID 24290Palladium Chloride
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 11287538tert-Butyl 4-(prop-2-yn-1-yl)piperazine-1-carboxylate
HCID 179681615-Bromo-4-(2,2-dimethylpropylamino)pyrimidine-2-carbonitrileProduct 1
Sources & evidence
- ORD record
- ord-c9d339f510e6419f8b0fa442b577e557
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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