HRID934783

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID81531

Diisopropylethylamine

C8H19N

HCID2773887

{4-[(Methanesulfonyl)amino]phenyl}acetic acid

C9H11NO4S

HCID16244559

未命名化合物

PRODUCTS

生成物

结构：CS(=O)(=O)Nc1ccc(CC(=O)NCC2CN(Cc3cccc(F)c3)CCO2)cc1

HCID21962840

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-714ae47779ea436bb520b89863af4d77
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:17][S:18](=[O:19])(=[O:20])[NH:21][c:22]1[cH:23][cH:24][c:25]([CH2:28][C:29](=[O:30])[OH:31])[cH:26][cH:27]1.[CH3:52][N:53]([CH3:54])[CH2:55][CH2:56][CH2:57][N:58]=[C:59]=[N:60][CH2:61][CH3:62].[CH3:63][N:64]([CH3:65])[CH:66]=[O:67].[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[ClH:51].[F:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH:8]([CH2:12][NH2:13])[O:9][CH2:10][CH2:11]2)[cH:14][cH:15][cH:16]1.[OH:32][n:33]1[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2[n:40][n:41]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH:8]([CH2:12][NH:13][C:29]([CH2:28][c:25]3[cH:24][cH:23][c:22]([NH:21][S:18]([CH3:17])(=[O:19])=[O:20])[cH:27][cH:26]3)=[O:30])[O:9][CH2:10][CH2:11]2)[cH:14][cH:15][cH:16]1