HRID937259

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID81531

Diisopropylethylamine

C8H19N

HCID14293429

2-(Aminooxy)-2-methylpropan-1-ol

C4H11NO2

HCID59565194

8-(4-Cyclopropyl-2-fluoro-phenylamino)-imidazo[1,5-a]pyridine-7-carboxylic acid

C17H14FN3O2

PRODUCTS

生成物

结构：CC(C)(CO)ONC(=O)c1ccn2cncc2c1Nc1ccc(C2CC2)cc1F

HCID44137227

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-393cc60dd9f848e1b6f46d950abf1a0d
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:24][CH2:25][N:26]=[C:27]=[N:28][CH2:29][CH2:30][CH2:31][N:32]([CH3:33])[CH3:34].[CH:1]1([c:4]2[cH:5][c:6]([F:23])[c:7]([NH:10][c:11]3[c:12]4[n:13]([cH:14][cH:15][c:16]3[C:17](=[O:18])[OH:19])[cH:20][n:21][cH:22]4)[cH:8][cH:9]2)[CH2:2][CH2:3]1.[CH:45]([N:46]([CH2:47][CH3:48])[CH:49]([CH3:50])[CH3:51])([CH3:52])[CH3:53].[ClH:54].[NH2:55][O:56][C:57]([CH2:58][OH:59])([CH3:60])[CH3:61].[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[OH:35][n:36]1[c:37]2[c:38]([cH:39][cH:40][cH:41][cH:42]2)[n:43][n:44]1>>[CH:1]1([c:4]2[cH:5][c:6]([F:23])[c:7]([NH:10][c:11]3[c:12]4[n:13]([cH:14][cH:15][c:16]3[C:17](=[O:19])[NH:55][O:56][C:57]([CH2:58][OH:59])([CH3:60])[CH3:61])[cH:20][n:21][cH:22]4)[cH:8][cH:9]2)[CH2:2][CH2:3]1