Cyanide → 5-Cyano-2-fluorobenzaldehyde

HRID 938353Notes

Reaction equation

HRID 938353 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:10])[c:6]([CH:7]=[O:8])[cH:9]1.[C-:22]#[N:23].[C-:25]#[N:26].[CH3:11][N:12]([CH3:13])[CH:14]=[O:15].[CH3:16][CH2:17][O:18][C:19](=[O:20])[CH3:21].[Zn+2:24]>>[c:2]1([C:11]#[N:12])[cH:3][cH:4][c:5]([F:10])[c:6]([CH:7]=[O:8])[cH:9]1

Participants

6

Reactant 5

HCID 5975Cyanide2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 32051Zinc(2+)HCID 7363275-Bromo-2-fluorobenzaldehyde

Product 1

HCID 109097255-Cyano-2-fluorobenzaldehyde

Sources & evidence

ORD record
ord-541ecc96e2e4401cbb02ab1a47afa739
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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