1,2-Dichloroethane → 3-amino-N-(2,4,6-trimethyl-3-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide
Reaction equation
[CH3:16][Al:17]([CH3:18])[CH3:19].[CH3:1][c:2]1[c:3]([NH2:4])[c:5]([CH3:15])[cH:6][c:7]([CH3:14])[c:8]1[N:9]1[CH2:10][CH2:11][CH2:12][CH2:13]1.[Cl:31][CH2:32][CH2:33][Cl:34].[ClH:30].[NH2:20][c:21]1[c:22]([C:26](=[O:27])[O:28][CH3:29])[s:23][cH:24][cH:25]1>>[CH3:1][c:2]1[c:3]([NH:4][C:26]([c:22]2[c:21]([NH2:20])[cH:25][cH:24][s:23]2)=[O:27])[c:5]([CH3:15])[cH:6][c:7]([CH3:14])[c:8]1[N:9]1[CH2:10][CH2:11][CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-91012f481d9b4f9d9bf22def3f5a33c6
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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