Hydrochloric Acid → N-Hydroxy-4-phenylbutanamide

HRID 951154Notes

Reaction equation

HRID 951154 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Cl:13][C:14]([O:15][CH2:16][CH3:17])=[O:18].[ClH:26].[K+:30].[NH2:27][OH:28].[OH-:29].[c:1]1([CH2:7][CH2:8][CH2:9][C:10](=[O:11])[OH:12])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][CH2:8][CH2:9][C:10](=[O:12])[NH:27][OH:28])[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 787HydroxylamineHCID 813Potassium CationHCID 961HydroxideHCID 47754-Phenylbutyric AcidHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 10928Ethyl chloroformate

Product 1

HCID 279980N-Hydroxy-4-phenylbutanamide

Sources & evidence

ORD record
ord-00c1ec272dd146b484137391b97fe349
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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