HRID954741

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID175

Acetate

C2H3O2-

2 次

HCID1049

Pyridine

C5H5N

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID8471

Triethylamine

C6H15N

HCID8857

Ethyl acetate

C4H8O2

HCID80271

Phosphine, tris(2-methylphenyl)-

C21H21P

HCID105144

Palladium(2+)

Pd+2

HCID2783168

5-Bromo-2-fluoropyridine

C5H3BrFN

HCID86663649

未命名化合物

PRODUCTS

生成物

HCID66821973

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-37cf033719c64f849b9c4dfc3b03ce1e
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:13][c:14]1[cH:15][cH:16][c:17]([F:20])[n:18][cH:19]1.[C:61]([O-:62])(=[O:63])[CH3:64].[C:66]([O-:67])(=[O:68])[CH3:69].[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[O:50]=[CH:51][N:52]([CH3:53])[CH3:54].[OH:1][CH:2]([C:3](=[O:4])[O:5][CH3:6])[CH2:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12].[Pd+2:65].[c:28]1([CH3:29])[cH:30][cH:31][cH:32][cH:33][c:34]1[P:35]([c:36]1[cH:37][cH:38][cH:39][cH:40][c:41]1[CH3:42])[c:43]1[cH:44][cH:45][cH:46][cH:47][c:48]1[CH3:49].[cH:70]1[cH:71][cH:72][n:73][cH:74][cH:75]1>>[OH:1][CH:2]([C:3](=[O:4])[O:5][CH3:6])[CH2:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH:12][c:14]1[cH:15][cH:16][c:17]([F:20])[n:18][cH:19]1